mTOR at the crossroads of T cell proliferation and tolerance
نویسندگان
چکیده
منابع مشابه
contribution of setting to the study of characters and the main idea in e. brontes: wuthering heights and t. hardys: return of the native.
this thesis aims to adduce an unmitigated and comprehensive explication concerning the relationship of three significant elements of fiction: setting, chracter and theme. my research is basically placed on two outstanding novels of the 19th century: emily brontes wuthering heights and thomas hardys return of the native. my endeavour lies in studying the correlation among the three above-mention...
15 صفحه اولEffects of valproic acid and pioglitazone on cell cycle progression and proliferation of T-cell acute lymphoblastic leukemia Jurkat cells
Objective(s): T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignant tumor. Administration of chemical compounds influencing apoptosis and T cell development has been discussed as promising novel therapeutic strategies. Valproic acid (VPA) as a recently emerged anti-neoplastic histone deacetylase (HDAC) inhibitor and pioglitazone (PGZ) as a high-affinity peroxisome p...
متن کاملmTOR-Dependent Cell Proliferation in the Brain
The mammalian Target of Rapamycin (mTOR) is a molecular complex equipped with kinase activity which controls cell viability being key in the PI3K/PTEN/Akt pathway. mTOR acts by integrating a number of environmental stimuli to regulate cell growth, proliferation, autophagy, and protein synthesis. These effects are based on the modulation of different metabolic pathways. Upregulation of mTOR asso...
متن کاملthe relationship between multiple intelligences and english proficiency of efl learners at payame noor university
این پژوهش برای بررسی پیوند احتمالی میان هوش های چندگانه – پیشنهاد شد? هاوارد گاردنر، 1983– (هم به گونه یکپارچه و هم به گونه بند بند) از یک سو و توانش انگلیسی دانشجویان ایرانی دانشگاه پیام نور در رشته زبان انگلیسی از سوی دیگر انجام گرفت. برای این کار، تافلpbt و پرسش نامه هوش های چندگانه میان 102 دانشجو در دانشگاه پیام نور شهریار پخش شد. نتایج بررسی داده ها نشان می دهد که در اندازه معنا داری 5 در...
15 صفحه اولleadership styles of tefl instructors at gilan university and their effects on the students attitudes and motivation
the subjects of the study are only the tefl teachers and students at gilan university. to obtain the desired data, a questionnaire which was based on the theories and disecussions gathered, was used as the main data gathering instrument. to determine the degree of relationship between variables, covariance and pearson product moment correlation coefficient were the formulas applied. the data we...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Seminars in Immunology
سال: 2007
ISSN: 1044-5323
DOI: 10.1016/j.smim.2007.02.008